2025 Global Down Syndrome Be Beautiful Be You

The Global Down Syndrome Foundation hosted its 18th annual Be Beautiful Be Yourself Fashion Show attracting over 1,400 guests from across the U.S. and around the world and raised $2.6 million.

Hollywood stars and self-advocates filled the red carpet in a powerful show of support for Global Down Syndrome Foundation. Among the notable attendees were Jessica BielJeremy RennerJane LynchKevin IannucciLauren Potter, John C. McGinley, Amanda BoothAlexis Floyd, Anthony Hill, Niko Terho, Sarah Bock, Max CarverShelley HennigBeverley MitchellMatthew Von Der Ahe, and James Day Keith, all united to champion GLOBAL’s mission to significantly improve the lives of people with Down syndrome through Research, Medical Care, Advocacy & Education.

Recognized as the largest and most celebrated Down syndrome fundraiser in the world, GLOBAL’s Be Beautiful Be Yourself Fashion Show has raised more than $33 million cumulatively since its inception, transforming research and tangible health outcomes for thousands of children and adults with Down syndrome.

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